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Cefspan 400mg tablets and syrup bottles displayed on a pharmacy counter in Pakistan

Cefspan Tablet Uses and Price in Pakistan

Introduction 

When you're feeling unwell with a stubborn infection, your doctor might prescribe an antibiotic to help your body fight back. One such commonly prescribed medication is Cefspan, a trusted name in antibiotics across Pakistan.

This blog will explore what Cefspan is, the various Cefspan tablet uses, and other key information you need to know. We will also cover its dosage and important safety precautions to ensure you use this medicine effectively and responsibly.

What is Cefspan? (Cefixime)

Cefspan is the brand name for the antibiotic Cefixime, a well-established third-generation cephalosporin used for treating a broad range of bacterial infections. As a prescription-only medication, it is commonly recommended when first-line antibiotics such as amoxicillin or co-trimoxazole are ineffective or when the infecting bacteria are known to be resistant.

Cefspan is available in multiple formulations, including 400 mg tablets for adults and older children and oral suspension for pediatric use. The suspension is offered in two strengths: the standard syrup and the more concentrated Cefspan DS (Double Strength) version, allowing doctors to adjust dosing more precisely for body weight and infection severity. Its flexible dosing options make it suitable for both mild and moderate infections across different age groups.

How Cefspan Works

Cefspan acts by binding to and inhibiting specific proteins (PBPs) involved in building the bacterial cell wall. Without an intact cell wall, bacteria lose their structural integrity, leading to cell rupture and death. This targeted mechanism makes cefixime effective against many gram-positive and gram-negative bacteria, including several strains responsible for respiratory, urinary, and gastrointestinal infections.

Another reason clinicians frequently choose Cefspan is its high oral bioavailability, meaning the body absorbs it efficiently. It also has a longer half-life compared to many antibiotics, allowing for once-daily dosing in many cases. This improves adherence to treatment, which is critical for preventing antibiotic resistance and ensuring complete eradication of the infection.

Cefspan Uses

Cefspan (cefixime) is prescribed to treat a variety of bacterial infections affecting the respiratory tract, urinary system, ears, throat, and gastrointestinal system. Its different formulations — tablet, regular syrup, and DS syrup — allow healthcare providers to tailor treatment based on patient age, weight, infection severity, and ability to swallow medication.

Difference between Cefspan Tablet, Syrup, and DS

Formulation

Uses

Notes

Cefspan Tablet (400 mg)

- Respiratory tract infections (bronchitis, pneumonia) - Throat infections (tonsillitis, pharyngitis) - Urinary tract infections (UTIs) - Uncomplicated gonorrhea* - Sinus infections - Typhoid fever (in areas with high antibiotic resistance)

*Cefixime for gonorrhea is now considered an alternative; intramuscular ceftriaxone is first-line where available. Tablets are for adolescents, adults, and older children who can swallow pills.

Cefspan Regular Syrup (100 mg/5 ml)

- Acute otitis media (ear infections) - Pediatric respiratory infections - Throat infections (tonsillitis/pharyngitis) - UTIs in children - Mild to moderate typhoid fever (weight-based)

Flexible dosing for infants and younger children; dose adjusted by weight.

Cefspan DS Syrup (200 mg/5 ml)

- Moderate to severe respiratory infections - Recurrent or persistent ear infections - Pediatric typhoid fever requiring higher dose - Older children who cannot take tablets

Delivers higher dose per mL for accurate weight-based dosing; useful for children who struggle with larger syrup volumes.

 

Who Should Not Use Cefspan 

Cefspan should not be used by people allergic to cefixime or other cephalosporins. Those with severe penicillin allergies may also face cross-reactive risks (see note).

Patients with kidney disease require dose adjustments, and dosing for infants must be precisely calculated based on weight.

Note: True cross-reaction between penicillins and third-generation cephalosporins is uncommon (estimates often 1–3%), so the risk is relatively low. Still, patients with a history of severe immediate penicillin allergy should be assessed by a clinician before cefixime is given.

Cefspan Tablet Dosage 

Standard Dosage for Children 

  • Usually given in syrup form.
  • Dosage is weight-based: around 8 mg/kg/day.
  • Can be given once daily or split into two doses.
  • Doctor decides between regular syrup and DS syrup based on severity and weight.
  • Always use the provided measuring device — never estimate doses.

Dosage for Adults & Adolescents 

  • Standard daily dose is 400 mg/day.
  • Can be taken as one 400 mg dose or two 200 mg doses.
  • DS syrup may be used if a liquid form is preferred.
  • Follow your doctor’s prescribed dosage without adjustments.

How to Take Cefspan 

  • Shake the syrup bottle for at least 10 seconds before use.
  • Use the measuring syringe/spoon provided.
  • Can be taken with or without food; food may reduce stomach upset.
  • Complete the full antibiotic course.
  • If you miss a dose, take it when remembered unless it’s close to the next dose.

Missed Dose Instructions 

If you miss a dose, take it as soon as possible unless it is nearly time for the next dose. Do not double the dose. Using reminders or alarms helps maintain consistent dosing.

Cefspan Tablet Price in Pakistan

Product Name

Quantity

Price (PKR)

Buy Link

Cefspan 400 mg Tablet

1 x 5 tablets

Rs. 730

Click here

Cefspan DS Suspension 200 mg/5 ml

1 x 30 ml

Rs. 501

Click here

Cefspan Regular Suspension 100 mg/5 ml

1 x 30 ml

Rs. 409

Click here

 

Cefspan Tablet Side Effects 

Common Side Effects 

  • Abdominal discomfort or stomach pain.
  • Mild diarrhea or loose stools.
  • Nausea or indigestion.
  • Headache.
  • Side effects are usually temporary and resolve as the body adjusts.

Serious Side Effects (When to See a Doctor)

  • Allergic reaction (rash, swelling, breathing difficulty).
  • Severe or persistent diarrhea (possible C. difficile infection).
  • Yellowing of eyes/skin, dark urine, unusual fatigue.
  • Worsening abdominal pain, high fever, or other severe symptoms.

Drug Interactions 

  • May increase effects of blood thinners (e.g., warfarin).
  • Possible interactions with carbamazepine or anticonvulsants.
  • Live oral vaccines (like typhoid) may become less effective.
  • Share your full medication list with your doctor.

Important Safety Advice 

Avoid unnecessary antibiotic use; Cefspan does not treat viral infections.
Complete the full treatment course to prevent resistance. Patients with kidney issues must inform their doctor for dose adjustments.

Conclusion 

Cefspan is a widely used antibiotic for various bacterial infections. Understanding the correct Cefspan tablet uses, dosage, side effects, and precautions ensures that the patient receives safe and effective treatment. Always use it under medical supervision and complete the prescribed course. Do not self medicate under any circumstance.

If you’re interested in further reading on health tips and medical products, check out our insightful health blogs.

FAQs 

1. What is Cefspan syrup used for?
Cefspan syrup treats bacterial infections in children, including ear, throat, chest, and urinary infections.

2. Is Cefspan good for fever or flu?
No; it works only for bacterial infections, not viral illnesses like flu.

3. What is the dosage of Cefspan syrup for kids?
Dose is weight-based (around 8 mg/kg/day) and must be prescribed by a pediatrician.

4. What are the side effects of Cefspan syrup?
Common effects include mild diarrhea, stomach discomfort, nausea, and headache.

5. Is Cefspan safe for typhoid?
Yes, it is commonly used for typhoid, but the antibiotic should be selected by a doctor based on resistance patterns.

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