BARIMOX TABLET 400 MG 5S

Moxifloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. By targeting these enzymes, moxifloxacin disrupts the supercoiling and separation of bacterial DNA strands, thereby preventing bacterial cell division and leading to cell death. This bactericidal action is effective against a wide range of Gram-positive and Gram-negative bacteria, as well as atypical pathogens. The enhanced activity of moxifloxacin against certain anaerobic bacteria and its high tissue penetration make it particularly useful in treating respiratory, skin, and intra-abdominal infections.

Moxifloxacin

Fluoroquinolone antibiotics

Tablet

Following are the precautions and warnings for SPF 50 Sunblock:

• Should not be used in individuals with a known allergy to any of the components of the sunscreen, including active ingredients like avobenzone, octinoxate, or oxybenzone.
• Caution is advised when using in patients with a history of skin sensitivities or allergies to sunscreen products.
• Avoid applying to broken, irritated, or sunburned skin, as this may increase irritation or discomfort.
• Do not apply near the eyes or mucous membranes; if accidental contact occurs, rinse thoroughly with water.
• Reapply sunscreen every two hours or after swimming, sweating, or towel drying to maintain protection.
• Avoid excessive sun exposure, even with sunscreen, and wear protective clothing, hats, and sunglasses when outdoors for prolonged periods.
• If any irritation, rash, or allergic reaction occurs after application, discontinue use and consult a healthcare provider.
• Consult a healthcare provider before using if you have any pre-existing skin conditions, such as eczema or rosacea.

In case of an overdose of Moxifloxacin Tablet, it is essential to seek immediate medical attention. Overdosing may increase the risk of adverse effects such as nausea, dizziness, confusion, and gastrointestinal disturbances. There is no specific antidote for Moxifloxacin overdose, so treatment focuses on managing symptoms. Activated charcoal may be administered to reduce the absorption of the drug if the overdose is recent, typically within an hour of ingestion. Supportive care, including monitoring of vital signs, fluid management, and treatment of any symptoms, may be required. In severe cases, medical professionals may perform gastric lavage or other procedures to manage the overdose. It is important not to self-manage an overdose and to contact a healthcare provider or poison control center for appropriate guidance.

If you miss a dose of Moxifloxacin Tablet, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for the missed dose, as this may increase the risk of side effects. If you are unsure about what to do or if you miss multiple doses, it is advisable to contact your healthcare provider for guidance. Maintaining a consistent dosing schedule is important to ensure the effectiveness of the medication and to avoid any complications.

To use Moxifloxacin Tablet, follow the instructions provided by your healthcare provider or as indicated on the prescription label. Typically, it should be taken once daily, with or without food. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet. It's important to take the medication at the same time each day to help you remember and maintain consistent levels in your body. Ensure you complete the full prescribed course of treatment, even if you start feeling better before finishing the medication, to prevent the infection from returning or developing resistance. If you have any questions about how to take this medicine, consult your healthcare provider.

Please take few things in consideration while taking Moxifloxacin Tablet:

• If you are allergic to moxifloxacin, any other quinolone antibiotics, or any of the ingredients in the tablet.
• If you have a history of tendon disorders or tendonitis related to the use of fluoroquinolone antibiotics.
• If you have a known or suspected history of QT interval prolongation or other heart problems, including arrhythmias.
• If you are pregnant or breastfeeding, unless specifically prescribed by your healthcare provider.
• If you are under 18 years of age, as safety and effectiveness in pediatric patients have not been established.
• If you have a history of severe hypersensitivity reactions, such as anaphylaxis or Stevens-Johnson syndrome, to moxifloxacin or other quinolones.
• If you are taking medications that may interact with moxifloxacin, such as certain antiarrhythmic drugs or other medications that affect the heart rhythm.

Discover the potential side effects associated with this medication as follows:

• Tendon pain, swelling, or rupture (especially in older adults or those taking corticosteroids)
• QT interval prolongation, which may lead to abnormal heart rhythms
• Severe allergic reactions, including anaphylaxis
• Liver problems, such as jaundice or abnormal liver function tests
• Severe gastrointestinal issues, including Clostridium difficile-associated diarrhea
• Seizures or convulsions
• Nerve damage (peripheral neuropathy)
• Mental health side effects, such as confusion, hallucinations, or depression
• Photosensitivity (increased sensitivity to sunlight)
• Muscle weakness or pain, particularly in those with myasthenia gravis
• Stevens-Johnson syndrome
• Toxic epidermal necrolysis
• Blood disorders, such as low white blood cell count or platelet count
• Kidney damage or changes in kidney function
• Eye problems, including blurred vision or other visual disturbances

Practice caution in case of use of Moxifloxacin Tablet:

• Known or suspected CNS disorders, or risk factors for seizures or lower seizure threshold.
• History or risk factors for QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, or cardiac disease (e.g., heart failure, MI, bradycardia).
• Positive family history of aneurysm disease, or pre-existing aortic aneurysm or dissection, including associated risk factors (e.g., Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease).
• Diabetes or history of tendon disorders (e.g., rheumatoid arthritis).
• G6PD deficiency.
• Renal or hepatic impairment.
• Elderly or children.
• Pregnancy or breastfeeding.
• Immunocompromised, febrile, or neutropenic condition.
• Treatment required for streptococcal infections or gonococcal infections (due to increasing quinolone-resistant N. gonorrhoeae globally).
• Treatment required for syphilis (as it is not effective).
• Treatment required for acute exacerbation of chronic bronchitis, acute uncomplicated cystitis, or acute sinusitis (only use if there are no alternative treatment options available).

Drug Interactions